I’m going to South Africa in March, 10 days starting in Johannesburg and then heading to Cape Town, planning to stay most of the trip in Cape Town. Any tips, suggestions, gems or things to avoid? For now, I only have the round-trip tickets to Johannesburg, the itinerary is still a white canvas. I’ll take a TR tour as well, but haven’t chosen yet.
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Do a few days in Kruger for the safari part and then fly down to Cape Town and would suggest doing a tour there. Earthstompers is an amazing provider to do the garden route 
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for what it’s worth, I booked this tour
i had booked this trip and was really good! 3 day Garden Route + Safari Highlights Tour from Cape Town by Hotspots2c with 83 Tour Reviews (Code: gr-saf3) - TourRadar 3 day Garden Route + Safari Highlights Tour from Cape Town by Hotspots2c
I would highly recommend checking out the penguins in Simons Town, hike up Table Mountain (or taking the cable car) and Lions Head and get a little tipsy in the Winelands in Franschhoek or Stellenbosch. 
If you need any recommendations on great wine farms , let me know!
If you want to avoid the crowds, then I can also highly recommend doing a small self-drive on the Garden Route with stops along Knysna, Tsitsikama and towards Port Elizabeth/Gqeberha.
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